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Compare tirzepatide programs and find the one that fits your goals and budget.
By the TreatmentMD editorial team
Why it's our #1 pick
By the TreatmentMD editorial team
Welludr. combines the lowest advertised tirzepatide price on this page, at every dose, with unlimited clinician messaging and a care coach, which is why it takes the top spot.
A program's rating follows its place on our list. Our editorial team sets the order, and the commission we earn affects it. How we rate
01What it is
Tirzepatide is the active ingredient in Zepbound®, which is FDA approved for weight management and for obstructive sleep apnea in adults with obesity. Mounjaro® contains it too, but is approved for type 2 diabetes. Both are weekly injections.
Tirzepatide also comes as compounded versions from state-licensed pharmacies, typically at a lower monthly cost. The 2024 to 2025 shortages are now resolved; compounded versions remain available through state-licensed (503A) pharmacies, prepared for an individual patient with a medical need the standard product doesn't meet.
02The evidence
In the main trial behind Zepbound®, people on the highest dose lost about 21% of their body weight over 72 weeks, compared with about 3% on a placebo. In the only trial to compare the two directly, which tirzepatide's maker funded, people lost about 20% on tirzepatide and about 14% on semaglutide.
These results belong to Zepbound®. Compounded tirzepatide has not been tested in trials.
03Choosing
Without insurance, Zepbound® costs $299 to $449 a month from its maker, rising with the dose. Some insurance plans cover it after a prior authorization.
Compounded tirzepatide starts at about $89 to $119 a month at our top three, with the medication included. Doses step up over several months, so a price that stays the same at every dose matters.
Provider review
Welludr. pairs compounded tirzepatide, at one price for every dose, with unlimited clinician messaging and a care coach, all managed online.
A short online health assessment is reviewed by a clinician licensed in your state, who decides whether treatment is right for you before any medication ships.
Medication ships free from a licensed Florida compounding pharmacy once a clinician approves you. Members get unlimited messaging with licensed clinicians, and a care coach who checks in every two weeks.
A month-to-month plan that renews every 21 days, or 3, 6 and 12-month plans paid up front. Stop a prepaid plan early and the months not yet started are refunded.
Provider review
Embody offers compounded tirzepatide at one price for every dose, with free coaching, free shipping and no membership fee.
A short online health questionnaire, reviewed by a licensed provider who decides whether treatment is appropriate.
Medication ships free, cold and overnight from licensed U.S. pharmacies; Embody says within two days of your prescription. It says its care team handles refills and dosing questions around the clock.
Month to month, or 3, 6 and 12-month plans paid up front for a lower rate. Cancel at least 72 hours before your next billing date.
Provider review
SnagRx offers compounded tirzepatide at one all-in price for every dose, with the online visit, medication and free shipping included.
A short online intake; SnagRx says a licensed clinician reviews it within 24 hours.
Free shipping from licensed U.S. 503A compounding pharmacies, with tracking; SnagRx says prescriptions received before 2pm Central ship the same day. The care team handles refills and dosing questions through the patient portal.
Month to month, or 3, 6 and 12-month plans for a lower rate. Payments are final, except a refund for the unused part of a plan if a provider decides you no longer qualify.
Zepbound® is FDA approved for long-term weight management and has been extensively studied for safety and efficacy.
The most common side effects are nausea, diarrhea, vomiting and constipation, mostly while your dose is rising, and they usually ease over time.
It carries a boxed warning about thyroid tumors seen in animal studies, and it is not for anyone with a personal or family history of medullary thyroid cancer or MEN 2, or who is pregnant.
Other warnings include pancreatitis and gallbladder problems, and a higher risk of low blood sugar when combined with insulin or a sulfonylurea.
It can make birth control pills less effective for four weeks after you start and after each dose increase, so ask your clinician about a backup method.
This is a high-level summary, not a complete list.
Compounded tirzepatide has not been reviewed by the FDA for safety or effectiveness.
A licensed clinician should decide whether treatment is right for you.
In the main trial behind Zepbound®, people lost about 15% of their body weight on average at the 5 mg dose and about 21% at 15 mg over 72 weeks, compared with about 3% on a placebo.
Your results depend on your dose, how long you stay on treatment and changes to diet and activity.
For weight loss alone, the evidence favors tirzepatide.
In the only trial to compare them directly, which tirzepatide's maker funded, people lost about 20% of their body weight on tirzepatide and about 14% on semaglutide over 72 weeks.
That trial did not include semaglutide's newer 7.2 mg dose.
Semaglutide also comes as a daily pill, and Wegovy® is approved to lower the risk of heart attack and stroke in people with heart disease, so your clinician can help you decide.
Without insurance, Zepbound® costs $299 to $449 a month from its maker, depending on the dose, as long as you refill within 45 days.
Compounded tirzepatide starts at about $89 to $119 a month at our top three programs, with the clinician and the medication included, and all three charge the same at every dose.
Some plans cover Zepbound® for weight loss or sleep apnea, usually after a prior authorization that checks your body mass index and related conditions.
Medicare's GLP-1 Bridge program covers the Zepbound® KwikPen for a $50 copay through December 2027, for people who qualify.
Compounded tirzepatide is almost never covered.
Of the programs above, Ro has an insurance team that checks private plans and files the paperwork for you.
Tirzepatide is meant for long-term use.
In a study where people stopped after about eight months, they regained much of the weight over the next year, while those who kept taking it lost more.
How long you stay on treatment is a decision to make with your clinician.
Our #1 pick
The lowest advertised tirzepatide price on our list, with unlimited clinician messaging.
